Research Topics
Head: PD Dr. Hans-Peter Mock
The Applied Biochemistry group aims at the identification of mechanisms regulating plant secondary metabolism.
Secondary metabolites significantly contribute to the interaction of plants with their environment, e.g. by acting as defence compounds. Plants synthesize a plethora of secondary compounds in response to stresses, and the accumulated substances can show anti-microbial properties, contribute to protection against UV and high light and act as antioxidants or signalling molecules.
The role of secondary compounds as part of the human nutrition is another important aspect. In cooperation with external partners the beneficial health effects of flavonoids as part of the human diet are investigated.
To identify regulatory factors which control the allocation of resources into different branches of secondary metabolism, the research group particularly uses metabolite profiling as well as proteome and transcriptome approaches. The functions of specific metabolites and proteins in the defence of abiotic or biotic stresses are investigated by using transgenic plants and mutants. Research is performed using the model plant Arabidopsis as well as barley, wheat and Solanaceous species. The spatial distribution of metabolites is visualized using MS-based approaches (MALDI-MS-Imaging).
A primary focus are the cellular responses of plants upon cold stress, which are analysed by metabolite analysis and molecular characterization of candidate genes. Techniques for metabolite profiling are also used to characterize accessions from the IPK seed collection. Further research aims at the characterization of candidate genes related to drought tolerance and N-efficiency in potato on the protein level.
The group has introduced techniques of proteome analysis as part of a functional genomics platform. They are based on the separation and mass spectrometrical detection of peptides after tryptic digestion of protein extracts. Proteome analysis includes post-translational modifications, e.g. phosphorylation. Data analysis is performed in close collaboration with bio-informatics groups.
Publications
Khoramizadeh F, Garibay-Hernández A, Mock H-P, Bilger W:
Improvement of the quality of wild rocket (Diplotaxis tenuifolia) with respect to health-related compounds by enhanced growth irradiance. J. Agric. Food Chem. 72 (2024) 9735–9745. https://dx.doi.org/10.1021/acs.jafc.3c07698
Nemati Z, Kazemi-Shahandashti S-S, Garibay-Hernández A, Mock H-P, Schmidt M H-W, Usadel B, Blattner F R:
Perez-Piñar T, Hartmann A, Bössow S, Gnad H, Mock H-P:
Leite Dias S, Garibay-Hernández A, Brendel F L, Chavez B G, Brückner E, Mock H-P, Franke J, D’Auria J C:
Saeid Nia M, Scholz L, Garibay-Hernández A, Mock H-P, Repnik U, Selinski J, Krupinska K, Bilger W:
Shanmugaraj N, Rajaraman J, Kale S, Kamal R, Huang Y, Thirulogachandar V, Garibay-Hernandez A, Budhagatapalli N, Tandron Moya Y A, Hajirezaei M R, Rutten T, Hensel G, Melzer M, Kumlehn J, von Wirén N, Mock H-P, Schnurbusch T:
Shanmugaraj N, Rutten T, Svatoš A, Schnurbusch T, Mock H-P:
Fast and reproducible matrix deposition for MALDI mass spectrometry imaging with improved glass sublimation setup. J. Am. Soc. Mass Spectrom. 34 (2023) 513-517. https://dx.doi.org/10.1021/jasms.2c00301
Wellpott K, Jozefowicz A M, Meise P, Schum A, Seddig S, Mock H-P, Winkelmann T, Bündig C:
Castellano M M, Ferrando A, Geisler M, Mock H-P, Muñoz A:
Gippert A-L, Madritsch S, Woryna P, Otte S, Mayrhofer M, Eigner H, Garibay-Hernández A, D’Auria J C, Molin E M, Mock H-P:
Grieco M, Schmidt M, Warnemünde S, Backhaus A, Klück H-C, Garibay A, Tandrón Moya Y A, Jozefowicz A M, Mock H-P, Seiffert U, Maurer A, Pillen K:
Meier A, Worch S, Hartmann A, Marzec M, Mock H-P, Bode R, Kunze G, Matthes F:
Characterization of catechol-1,2-dioxygenase (Acdo1p) from Blastobotrys raffinosifermentans and investigation of its role in the catabolism of aromatic compounds. Front. Microbiol. 13 (2022) 872298. https://dx.doi.org/10.3389/fmicb.2022.872298
Cenk E, Schmutz C, Pahlke G, Oertel A, Kollarova J, Mock H-P, Matros A, Marko D:
Dreyer A, Treffon P, Basiry D, Jozefowicz A M, Matros A, Mock H-P, Dietz K-J:
Garibay-Hernández A, Kessler N, Józefowicz A M, Türksoy G M, Lohwasser U, Mock H-P:
Jardak R, Riahi J, Dallagi W, Planchon S, Boubakri H, Bouamama B, Bouagila A, Nefissi R, Mejri S, Renaut J, Mock H P, Ghorbel A:
Pahlke G, Ahlberg K, Oertel A, Janson-Schaffer T, Grabher S, Mock H-P, Matros A, Marko D:
Antioxidant effects of elderberry anthocyanins in human colon carcinoma cells: a study on structure-activity relationships. Mol. Nutr. Food Res. 65 (2021) 2100229. https://dx.doi.org/10.1002/mnfr.202100229
Witzel K, Matros A, Bertsch U, Aftab T, Rutten T, Ramireddy E, Melzer M, Kunze G, Mock H-P:
Jozefowicz A M, Döll S, Mock H P:
Proteomic approaches to identify proteins responsive to cold stress. In: Hincha D, Zuther E (Eds.): Plant cold acclimation. Methods and protocols. (Series: Methods in molecular biology, Vol. 2156) New York, NY: Humana Press (2020) 1940-6029 (Electronic)1064-3745 (Linking), 161-170. https://dx.doi.org/10.1007/978-1-0716-0660-5_12
Liebthal M, Schuetze J, Dreyer A, Mock H P, Dietz K J:
Lim W L, Collins H M, Byrt C S, Lahnstein J, Shirley N J, Aubert M K, Tucker M R, Peukert M, Matros A, Burton R A:
Overexpression of HvCslF6 in barley grain alters carbohydrate partitioning plus transfer tissue and endosperm development. J. Exp. Bot. 71 (2020) 138–153. https://dx.doi.org/10.1093/jxb/erz407
Nazir F, Fariduddin Q, Khan T A:
Phytochemische und molekulare Untersuchungen zur Regulation der Anthocyanbiosynthese in verschiedenfarbigen tetraploiden Kartoffelakzessionen (Solanum tuberosum L.) und die Rolle der Flavonoid-3´,5´-hydroxylase. (PhD Thesis, kumulativ) Kiel, Christian-Albrechts-Universität zu Kiel, Mathematisch-Naturwissenschaftliche Fakultät (2020)
Schubert R, Werner S, Cirka H, Rödel P, Tandron Moya Y, Mock H P, Hutter I, Kunze G, Hause B:
Stock J, Bräutigam A, Melzer M, Bienert G P, Bunk B, Nagel M, Overmann J, Keller E R J, Mock H P:
Wimmer M A, Abreu I, Bell R W, Bienert M D, Brown P H, Dell B, Fujiwara T, Goldbach H E, Lehto T, Mock H-P, von Wirén N, Bassil E, Bienert G P:
Xu D, Dhiman R, Garibay A, Mock H P, Leister D, Kleine T:
Capdesuner Y, Garcia-Brizuela J, Mock H P, Hernandez K V, de la Torre M H, Santiesteban-Toca C E:
Frank S, Hollmann J, Mulisch M, Matros A, Carrión C C, Mock H P, Hensel G, Krupinska K:
Hussain M, Khan T A, Yusuf M, Fariduddin Q:
Key mechanisms leading to the contrasting nitrogen deficiency response in a pair of potato cultivars. (PhD Thesis, kumulativ) Kiel, Christian-Albrechts-Universität zu Kiel, Mathematisch-Naturwissenschaftliche Fakultät (2019)
Khan T A, Yusuf M, Ahmad A, Bashir Z, Saeed T, Fariduddin Q, Hayat S, Mock H P, Wu T:
Proteomic and physiological assessment of stress sensitive and tolerant variety of tomato treated with brassinosteroids and hydrogen peroxide under low-temperature stress. Food Chem. 289 (2019) 500-511. https://dx.doi.org/10.1016/j.foodchem.2019.03.029
Study of the metabolism during microspore embryogenesis in wheat DH lines using-omics approaches. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2019) 102 pp.
Riahi J, Amri B, Chibani F, Azri W, Mejri S, Bennani L, Zoghlami N, Matros A, Mock H P, Ghorbel A, Jardak R:
Comparative analyses of albumins/globulins grain proteome fraction in differentially salt tolerant Tunisian barley landraces reveals genotype-specific and defined abundant proteins. Plant Biol. 21 (2019) 652-661. https://dx.doi.org/10.1111/plb.12965
Shen S, Ma S, Liu Y H, Liao S J, Li J, Wu L M, Kartika D, Mock H P, Ruan Y L:
Cell wall invertase and sugar transporters are differentially activated in tomato styles and ovaries during pollination and fertilization. Front. Plant Sci. 10 (2019) 506. https://dx.doi.org/10.3389/Fpls.2019.00506
Stelzner J, Roemhild R, Garibay-Hernandez A, Harbaum-Piayda B, Mock H P, Bilger W:
Stock J, Mock H-P, Senula A, Nagel M:
Arabidopsis – a model to elucidate complex stress response mechanism during cryopreservation. In: Thammasiri K, Kongsawadworakul P, Pritchard H W (Eds.): Proceedings of the III International Symposium on Plant Cryopreservation: Bangkok, Thailand, March 26-28, 2018. (Series: Acta Horticulturae, Vol. 1234) Leuven: ISHS (2019) 85-96. https://dx.doi.org/10.17660/ActaHortic.2019.1234.11
Tomay F, Marinelli A, Leoni V, Caccia C, Matros A, Mock H P, Tonelli C, Petroni K:
Wu J, Mock H P, Giehl R F H, Pitann B, Mühling K H:
Xue C, Matros A, Mock H P, Mühling K H:
Appelhagen I, Wulff-Vester A K, Wendell M, Hvoslef-Eide A K, Russell J, Oertel A, Martens S, Mock H-P, Martin C, Matros A:
Bajerski F, Stock J, Hanf B, Darienko T, Heine-Dobbernack E, Lorenz M, Naujox L, Keller E R J, Schumacher H M, Friedl T, Eberth S, Mock H P, Kniemeyer O, Overmann J:
Barkla B J, Garibay-Hernández A, Melzer M, Rupasinghe T W T, Roessner U:
Single cell-type analysis of cellular lipid remodelling in response to salinity in the epidermal bladder cells of the model halophyte Mesembryanthemum crystallinum. Plant Cell Environ. 41 (2018) 2390-2403. https://dx.doi.org/10.1111/pce.13352
Brauch D, Porzel A, Schumann E, Pillen K, Mock H-P:
Döll S, Kuhlmann M, Rutten T, Mette M F, Scharfenberg S, Petridis A, Berreth D C, Mock H-P:
Accumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex. Plant J. 93 (2018) 431-444. https://dx.doi.org/10.1111/tpj.13797
Fernández-Bautista N, Fernández-Calvino L, Muñoz A, Toribio R, Mock H-P, Castellano M M:
Hartmann A, Jozefowicz A M:
VANTED: a tool for integrative visualization and analysis of -omics data. In: Mock H P, Matros A, Witzel K (Eds.): Plant Membrane Proteomics: Methods and Protocols. (Series: Methods in molecular biology, Vol. 1696) New York, NY: Humana Press (2018) ISBN 978-1-4939-7409-2, 261-278. https://dx.doi.org/10.1007/978-1-4939-7411-5_18
Jozefowicz A M, Matros A, Witzel K, Mock H-P:
Mini-scale isolation and preparation of plasma membrane proteins from potato roots for LC/MS Analysis. In: Mock H P, Matros A, Witzel K (Eds.): Plant Membrane Proteomics: Methods and Protocols. (Series: Methods in molecular biology, Vol. 1696) New York, NY: Humana Press (2018) ISBN 978-1-4939-7409-2, 195-204. https://dx.doi.org/10.1007/978-1-4939-7411-5_13
Köpnick C, Grübe M, Stock J, Senula A, Mock H-P, Nagel M:
Mock H-P, Finnie C, Witzel K, Svensson B:
Barley proteomics. In: Stein N, Muehlbauer G J (Eds.): The Barley Genome, 1st ed. (Series: Kole, C (Ed.): Compendium of Plant Genomes) Cham: Springer (2018) ISBN 978-3-319-92528-8, 345-361. https://dx.doi.org/10.1007/978-3-319-92528-8_19
Mock H-P, Matros A, Witzel K (Eds.):
Cellular stress responses during cryo-induced stress in Arabidopsis shoot tips. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2018) 76 pp.
Witzel K, Matros A, Møller A L B, Ramireddy E, Finnie C, Peukert M, Rutten T, Herzog A, Kunze G, Melzer M, Kaspar-Schoenefeld S, Schmülling T, Svensson B, Mock H-P:
Plasma membrane proteome analysis identifies a role of barley Membrane Steroid Binding Protein in root architecture response to salinity. Plant Cell Environ. 41 (2018) 1311-1330. https://dx.doi.org/10.1111/pce.13154
Wu J, Mock H P, Mühling K H:
Bilova T, Paudel G, Shilyaev N, Schmidt R, Brauch D, Tarakhovskaya E, Milrud S, Smolikova G, Tissier A, Vogt T, Sinz A, Brandt W, Birkemeyer C, Wessjohann L A, Frolov A:
Global proteomic analysis of advanced glycation end products in the Arabidopsis proteome provides evidence for age-related glycation hot spots. J. Biol. Chem. 292 (2017) 15758-15776. https://dx.doi.org/10.1074/jbc.M117.794537
Eisenabhängige Suberin- und Cumarinsynthese in Arabidopsis thaliana und Nicotiana tabacum. (Bachelor Thesis) Mittweida, Hochschule Mittweida (2017) 57 pp.
Jozefowicz A M, Hartmann A, Matros A, Schum A, Mock H-P:
Nitrogen deficiency induced alterations in the root proteome of a pair of potato (Solanum tuberosum L.) varieties contrasting for their response to low N. Proteomics 17 (2017) 1700231. https://dx.doi.org/10.1002/pmic.201700231
Knauer U, Matros A, Petrovic T, Zanker T, Scott E S, Seiffert U:
Lamm C E, Kraner M E, Hofmann J, Börnke F, Mock H-P, Sonnewald U:
Matros A, Liu G, Hartmann A, Jiang Y, Zhao Y, Wang H, Ebmeyer E, Korzun V, Schachschneider R, Kazman E, Schacht J, Longin F, Reif J C, Mock H-P:
Genome-metabolite associations revealed low heritability, high genetic complexity, and causal relations for leaf metabolites in winter wheat (Triticum aestivum). J. Exp. Bot. 68 (2017) 415-428. https://dx.doi.org/10.1093/jxb/erw441
Meise P, Jozefowicz A M, Uptmoor R, Mock H-P, Ordon F, Schum A:
Nawrot R, Lippmann R, Matros A, Musidlak O, Nowicki G, Mock H-P:
Oertel A, Matros A, Hartmann A, Arapitsas P, Dehmer K J, Martens S, Mock H-P:
Petroni K, Trinei M, Fornari M, Calvenzani V, Marinelli A, Micheli L A, Pilu R, Matros A, Mock H-P, Tonelli C, Giorgio M:
Radchuk V, Riewe D, Peukert M, Matros A, Strickert M, Radchuk R, Weier D, Steinbiß H-H, Sreenivasulu N, Weschke W, Weber H:
Down-regulated sucrose transporters HvSUT1, HvSUT2 affects sucrose homeostasis along its delivery path in barley grains. J. Exp. Bot. 68 (2017) 4595-4612. https://doi.org/10.1093/jxb/erx266
Soleimani B, Sammler R, Backhaus A, Beschow H, Schumann E, Mock H-P, von Wirén N, Seiffert U, Pillen K:
Genetic regulation of growth and nutrient content under phosphorus deficiency in the wild barley introgression library S42IL. Plant Breed. 136 (2017) 892-907. https://dx.doi.org/10.1111/pbr.12540
Stock J, Senula A, Nagel M, Mock H-P, Keller E R J:
A simple method for shoot tip cryopreservation of Arabidopsis genotypes. Cryo Lett. 38 (2017) 364-371.
Physiological, phytochemical and molecular characterization of pigmented cereals. (PhD Thesis) Kiel, Christian-Albrechts-Universität zu Kiel (2017) 140 pp.
Studies of the sugarbeet leaf metabolome and ist hyperspectral reflectance signature responding to environmental stress. (PhD Thesis, kumulativ) Kiel, Christian-Albrechts-Universität zu Kiel (2016)
Arens N, Backhaus A, Döll S, Fischer S, Seiffert U, Mock H-P:
Bündig C, Jozefowicz A M, Mock H-P, Winkelmann T:
Fíla J, Radau S, Matros A, Hartmann A, Scholz U, Feciková J, Mock H-P, Ĉapková V, Zahedi R P, Honys D:
Untersuchungen zum Carotinoid-Spektrum von Tomaten aus verschiedenen Solanum lycopersicum Genbank-Akzessionen. (Master Thesis) Köthen, Hochschule Anhalt (2016) 71 pp.
Kaspar-Schoenefeld S, Merx K, Jozefowicz A M, Hartmann A, Seiffert U, Weschke W, Matros A, Mock H-P:
Keller E R J, Grübe M, Hajirezaei M-R, Melzer M, Mock H-P, Rolletschek H, Senula A, Subbarayan K:
Experience in large-scale cryopreservation and links to applied research for safe storage of plant germplasm. In: Lambardi M, Hamill S (Eds.): Proceedings of the XXIX IHC - Int. Symp. on Micropropagation and In Vitro Techniques, Brisbane, Australia, August 17-22, 2014. (Series: Acta Horticulturae, Vol. 1113) Leuven: ISHS (2016) 239-249. https://dx.doi.org/10.17660/ActaHortic.2016.1113.36
Meise P, Seddig S, Schum A, Josefowicz A, Mock H-P, Dehmer K, Bündig C, Winkelmann T:
Trocken- und Stickstoffmangel – Stressreaktionen der Stärkekartoffel. Untersuchungen auf morphologischer, physiologischer und proteomischer Ebene im Projekt PROKAR. Kartoffelbau 67 (2016) 40-45.
Special Issue: Plant Proteomics: a bridge between fundamental processes and crop production. (Series: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol. 1864, No. 8) (2016) 179 pp.
Nawrot R, Barylski J, Lippmann R, Altschmied L, Mock H-P:
Petridis A, Döll S, Nichelmann L, Bilger W, Mock H-P:
Arabidopsis thaliana G2-LIKE FLAVONOID REGULATOR and BRASSINOSTEROID ENHANCED EXPRESSION1 are low-temperature regulators of flavonoid accumulation. New Phytol. 211 (2016) 912-925. https://dx.doi.org/10.1111/nph.13986
Peukert M, Dittbrenner A, Meinhard J, Fischer U, Mock H-P:
Peukert M, Thiel J, Mock H-P, Marko D, Weschke W, Matros A:
Shoeva O Y, Mock H-P, Kukoeva T V, Börner A, Khlestkina E K:
A proteomic view of the cereal and vegetable crop response to salinity stress. In: Salekdeh G H (Ed.): Agricultural proteomics, Vol. 2, Environmental stresses. Cham: Springer (2016) ISBN 978-3-319-43276-2, 53-69. https://doi.org/10.1007/978-3-319-43278-6_3
Arens N, Döll S, Mock H-P:
The reproducibility of liquid chromatography separation technology and its potential impact on large scale plant metabolomics experiments. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 991 (2015) 41-45. https://dx.doi.org/10.1016/j.jchromb.2015.04.005
Lippmann R, Friedel S, Mock H-P, Kumlehn J:
Matros A, Peshev D, Peukert M, Mock H-P, van den Ende W:
Tohge T, Zhang Y, Peterek S, Matros A, Rallapalli G, Tandrón Y A, Butelli E, Kallam K, Hertkorn N, Mock H-P, Martin C, Fernie A R:
Ectopic expression of snapdragon transcription factors facilitates the identification of genes encoding enzymes of anthocyanin decoration in tomato. Plant J. 83 (2015) 686-704. https://dx.doi.org/10.1111/tpj.12920
Zhao Y, Li Z, Liu G, Jiang Y, Maurer H P, Würschum T, Mock H-P, Matros A, Ebmeyer E, Schachschneider R, Kazman E, Schacht J, Gowda M, Longin C F, Reif J C:
Arens N, Döll S, Mock H-P:
LC and LC–MS: techniques and applications. In: Meyers R A (Ed.): Encyclopedia of analytical chemistry. Chichester [u.a.]: John Wiley and Sons, Ltd (2014) Online ISBN 978-0-470-02731-8, 1-9. https://dx.doi.org/10.1002/9780470027318.a9912
Döll S, Lippmann R, Mock H-P:
Proteomic approaches to identify cold-regulated soluble proteins. In: Hincha D K, Zuther E (Eds.): Plant cold acclimation: methods and protocols. (Series: Methods in molecular biology, Vol. 1166) New York [u.a.]: Humana Press (2014) ISBN 978-1-4939-0843-1, 139-158. https://dx.doi.org/10.1007/978-1-4939-0844-8_12
Huerta-Ocampo J A, Barrera-Pacheco A, Mendoza-Hernández C S, Espitia-Rangel E, Mock H-P, Barba de la Rosa A P:
Janmohammadi M, Mock H-P, Matros A:
Proteomic analysis of cold acclimation in winter wheat under field conditions. Iceland. Agr. Sci. 27 (2014) 3-15.
Etablierung und Optimierung einer gaschromatographischen Methode zur Analyse von flüchtigen Verbindungen aus Zuckerrübensaatgut. (Master Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg (2014) 109 pp.
Neumann G, Bott S, Ohler M A, Mock H-P, Lippmann R, Grosch R, Smalla K:
Peukert M, Becker M, Matros A, Mock H-P:
Mass spectrometry based imaging of metabolites and proteins. In: Jorrin-Novo J V, Komatsu S, Weckwerth W, Wienkoop S (Eds.): Plant proteomics: methods and protocols. (Series: Methods in molecular biology, Vol. 1072) New York [u.a.]: Humana Press (2014) ISBN 978-1-62703-630-6, 223-240. https://dx.doi.org/10.1007/978-1-62703-631-3_17
Peukert M, Thiel J, Peshev D, Weschke W, Van den Ende W, Mock H-P, Matros A:
Schmid N B, Giehl R F, Döll S, Mock H-P, Strehmel N, Scheel D, Kong X, Hider R C, von Wirén N:
Trautwein-Schult A, Jankowska D, Cordes A, Hoferichter P, Klein C, Matros A, Mock H-P, Baronian K, Bode R, Kunze G:
Arxula adeninivorans recombinant guanine deaminase and its application in the production of food with low purine content. J. Mol. Microbiol. Biotechnol. 24 (2014) 67-81. https://dx.doi.org/10.1159/000357674
Witzel K, Matros A, Strickert M, Kaspar S, Peukert M, Mühling K H, Börner A, Mock H-P:
Salinity stress in roots of contrasting barley genotypes reveals time-distinct and genotype-specific patterns for defined proteins. Mol. Plant 7 (2014) 336-355. https://dx.doi.org/10.1093/mp/sst063
Agarwal R, Matros A, Melzer M, Mock H-P:
Blue-native page analysis validates heterogeneity in the thylakoids of Synechocystis 6803. In: Kuang T, Lu C, Zhang L (Eds.): Photosynthesis research for food, fuel and the future: 15th International Conference on Photosynthesis, Beijing, China, August 22 - 27, 2010. (Series: Advanced topics in science and technology in China) Heidelberg [u.a.]: Springer (2013) ISBN 978-3-642-32033-0, 385-388. https://dx.doi.org/10.1007/978-3-642-32034-7_80
Barkla B J, Castellanos-Cervantes T, Diaz de León J L, Matros A, Mock H-P, Perez-Alfocea F, Salekdeh G H, Witzel K, Zörb C:
Elucidation of salt stress defense and tolerance mechanisms of crop plants using proteomics - current achievements and perspectives. Proteomics 13 (2013) 1885-1900. https://dx.doi.org/10.1002/pmic.201200399
Studies on scopolin and scopoletin - stress-induced accumulation and regulatory elements. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2013) 196 pp.
Gutierrez-Carbonell E, Lattanzio G, Sagardoy R, Rodríguez-Celma J, Ríos Ruiz J J, Matros A, Abadía A, Abadía J, López-Millán A F:
Lattanzio G, Andaluz S, Matros A, Calvete J J, Kehr J, Abadía A, Abadía J, López-Millán A F:
Muthuramalingam M, Matros A, Scheibe R, Mock H-P, Dietz K J:
Spatiotemporal distributions of metabolites involved in barley grain development with emphasis on endosperm formation. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2013) 196 pp.
Peukert M, Weise S, Röder M S, Matthies I E:
MALDI mass spectrometric imaging of plants. In: Weckwerth W, Kahl G (Eds.): The handbook of plant metabolomics. (Series: Molecular plant biology handbook) Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA (2013) ISBN 978-3-527-32777-5, 93-110. https://dx.doi.org/10.1002/9783527669882.ch5
Trautwein-Schult A, Jankowska D, Cordes A, Hoferichter P, Klein C, Matros A, Mock H-P, Baronian K, Bode R, Kunze G:
Arxula adeninivorans recombinant urate oxidase and its application in the production of food with low uric acid content. J. Mol. Microbiol. Biotechnol. 23 (2013) 418-430. https://dx.doi.org/10.1159/000353847
Identifizierung von Metaboliten der Gerste zur Charakterisierung der Salzstressabwehr. (Bachelor Thesis) Köthen, Hochschule Anhalt (FH) (2013) 77 pp.
Proteomanalysen des Kavernensaftes in Gerstensamen. (Bachelor Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2013) 45 pp.
Untersuchungen zum Phosphoproteinmuster von Gerstenwurzeln bei Salzstress. (Bachelor Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2013) 45 pp.
Molekularbiologische und phytochemische Untersuchungen in Trichomen verschiedener Nicotiana tabacum Genbank-Akzessionen mit besonderer Betrachtung von Genen des Sekundärmetabolismus. (Diploma Thesis) Kassel, Universität Kassel, Fachbereich 10 Mathematik und Naturwissenschaften (2012) 100 pp.
Capanoglu E, Beekwilder J, Matros A, Boyacioglu D, Hall R D, Mock H-P:
Correlation of rutin accumulation with 3-O-glucosyl transferase and phenylalanine ammonia-lyase activities during the ripening of tomato fruit. Plant Foods Hum. Nutr. 67 (2012) 371-376. https://dx.doi.org/10.1007/s11130-012-0321-1
Fila J, Matros A, Radau S, Zahedi R P, Čapková V, Mock H-P, Honys D:
Biochemische und molekulare Untersuchungen der HOP/STI1 Proteinfamilie in Pflanzen. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2012) 127 pp.
Janiak A, Piórko S, Matros A, Mock H-P, Kwaśniewski M, Chwialkowska K, Chmielewska B, Szarejko I:
A comparative analysis of proteins that accumulate during the initial stage of root hair development in barley root hair mutants and their parent varieties. J. Appl. Genet. 53 (2012) 363-376. https://dx.doi.org/10.1007/s13353-012-0105-1
Physiologische und bioanalytische Untersuchungen während der Pollenembryogenese von Hordeum vulgare. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg, Naturwissenschaftliche Fakultät I Biowissenschaften (2012) 149 pp.
Martin C, Jie L, Lebouteiller B, Mock H-P, Matros A, Peterek S, Schijlen E G W M, Hall R, Shintu L, Colquhoun I, Weisshaar B, Butelli E:
Combining genomics and metabolomics for the discovery of regulatory genes and their use in metabolic engineering to produce healthy foods. In: Hvoslef-Eide A K (Ed.): Proceedings of the Ist International Symposium on Genetic Modifications - Challenges and Opportunitiesfor Horticulture in the World: Ski, Norway, September 16 - 20, 2007. (Series: Acta Horticulturae, Vol. 941) Leuven: ISHS (2012) 2406-6168, 73-84. https://dx.doi.org/10.17660/ActaHortic.2012.941.4
Melonek J, Matros A, Trösch M, Mock H-P, Krupinska K:
Mock H-P, Wang Z Y, Komatsu S (Eds.):
Frontiers in Agriculture Proteome Research: Contribution of Proteomics Technology in Agricultural Sciences: Proceedings of the 3rd International Symposium on Frontiers in Agriculture Proteome Research. Tsukuba: NARO Institute of Crop Science (2012) ISBN 978-4-904633-99-1, 143 pp.
Peukert M, Matros A, Dittbrenner A, Seiffert U, Mock H-P:
Mass spectrometry based imaging in plant science: current status and perspectives. In: Mock H P, Wang Z Y, Komatsu S (Eds.): Frontiers in Agriculture Proteome Research: Contribution of Proteomics Technology in Agricultural Sciences: Proceedings of the 3rd International Symposium on Frontiers in Agriculture Proteome Research. Tsukuba: NARO Institute of Crop Science (2012) ISBN 978-4-904633-99-1, 3-6.
Peukert M, Matros A, Lattanzio G, Kaspar S, Abadia J, Mock H-P:
Riewe D, Koohi M, Lisec J, Pfeiffer M, Lippmann R, Schmeichel J, Willmitzer L, Altmann T:
Bazargani M M, Sarhadi E, Bushehri A A, Matros A, Mock H-P, Naghavi M R, Hajihoseini V, Mardi M, Hajirezaei M-R, Moradi F, Ehdaie B, Salekdeh G H:
Analyse der gewebespezifischen Expression von Genen der Stressabwehr in Arabidopsis-Wurzeln mit besonderer Berücksichtigung von Genen des Phenylpropanstoffwechsels. (Master Thesis) Hohenheim, Fakultät Naturwissenschaften, Universität Hohenheim (2011) 99 pp.
Analysis of isolated barley tissues using proteomic approaches. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg (2011) 224 pp.
Kaspar S, Peukert M, Svatos A, Matros A, Mock H-P:
Modifikation von Anthocyanseitenketten mit Hilfe rekombinant exprimierter Proteine. (Bachelor Thesis) Köthen, Hochschule Anhalt (2011) 75 pp.
Matros A, Kaspar S, Tenzer S, Kipping M, Seiffert U, Mock H-P:
Label-free liquid chromatography-based quantitative proteomics: challenges and recent developments. In: Rancourt G C (Ed.): Proteomics: methods, applications and limitations. (Series: Protein biochemistry, synthesis, structure and cellular functions) Hauppauge, N.Y., USA: Nova Science Publishers (2011) ISBN 978-1-61668-691-8, 103-136.
Matros A, Kaspar S, Witzel K, Mock H-P:
Møller A L B, Witzel K, Vertommen A, Barkholt V, Svennson B, Carpentier S, Mock H-P, Finnie C:
Plant plasma membrane proteomics: challenges and possibilities. In: Ivanov A R, Lazarev A V (Eds.): Sample preparation in biological mass spectrometry. Dordrecht [u.a.]: Springer (2011) ISBN 978-94-0070758-0, 411-434. https://dx.doi.org/10.1007/978-94-007-0828-0_21
Witzel K, Pietsch C, Strickert M, Matros A, Röder M, Weschke W, Wobus U, Mock H-P:
Witzel K, Shahzad M, Matros A, Mock H-P, Mühling K H:
Agarwal R, Matros A, Melzer M, Mock H-P, Sainis J K:
Expression differencial de proteinas radiculares del trigo (Triticum aestivum L.) a la adhesion de Azospirillum brasiliense Cd. (Master Thesis) La Paz/Mexico (2010) 105 pp.
Kaspar S, Matros A, Mock H-P:
Proteome and flavonoid analysis reveals distinct responses of epidermal tissue and whole leaves upon UV-B radiation of barley (Hordeum vulgare L.) seedlings. J. Proteome Res. 9 (2010) 2402-2411. https://dx.doi.org/10.1021/pr901113z
Kaspar S, Weier D, Weschke W, Mock H-P, Matros A:
Protein analysis of laser capture micro-dissected tissues revealed cell-type specific biological functions in developing barley grains. Anal. Bioanal. Chem. 398 (2010) 2883-2893. https://dx.doi.org/10.1007/s00216-010-4120-y
Seiffert U, Bollenbeck F, Mock H-P, Matros A:
Clustering of crop phenotypes by means of hyperspectral signatures using artificial neural networks. In: IEEE (Ed.): 2010 2nd Workshop on Hyperspectral Image and Signal Processing: Evolution in Remote Sensing (WHISPERS 2010), Reykjavik, Iceland, 14 - 16 June 2010. Piscataway, NJ: IEEE Press (2010) ISBN 978-1-4244-8906-0, 31-34. https://dx.doi.org/10.1109/WHISPERS.2010.5594947
Sreenivasulu N, Borisjuk L, Junker B H, Mock H-P, Rolletschek H, Seiffert U, Weschke W, Wobus U:
Witzel K, Weidner A, Surabhi G K, Varshney R K, Kunze G, Buck-Sorlin G H, Börner A, Mock H-P:
Böer E, Bode R, Mock H-P, Piontek M, Kunze G:
Atan1p - an extracellular tannase from the dimorphic yeast Arxula adeninivorans: molecular cloning of the ATAN1 gene and characterization of the recombinant enzyme. Yeast 26 (2009) 323-337. https://dx.doi.org/10.1002/yea.1669
Bollenbeck F, Kaspar S, Mock H-P, Weier D, Seiffert U:
Three-dimensional multimodality modelling by integration of high-resolution interindividual atlases and functional MALDI-IMS data. In: Rajasekaran S (Ed.): Bioinformatics and computational biology: first international conference, BICoB 2009, New Orleans, LA, USA, April 8-10, 2009; proceedings. (Series: Lecture Notes in Computer Science, Vol. 5462) Berlin [u.a.]: Springer (2009) ISBN 978-3-642-00726-2, 126-138. https://dx.doi.org/10.1007/978-3-642-00727-9_14
Dittbrenner A, Mock H-P, Börner A, Lohwasser U:
Variability of alkaloid content in Papaver somniferum L. J. Appl. Bot. Food Qual. 82 (2009) 103-107.
Jahn D, Matros A, Bakulina A Y, Tiedemann J, Schubert U, Giersberg M, Haehnel S, Zoufal K, Mock H-P, Kipriyanov S M:
Model structure of the immunodominant surface antigen of Eimeria tenella identified as a target for sporozoite-neutralizing monoclonal antibody. Parasitol. Res. 105 (2009) 655-668. https://dx.doi.org/10.1007/s00436-009-1437-6
Lippmann R, Kaspar S, Rutten T, Melzer M, Kumlehn J, Matros A, Mock H-P:
Protein and metabolite analysis reveals permanent induction of stress defense and cell regeneration processes in a tobacco cell suspension culture. Int. J. Mol. Sci. 10 (2009) 3012-3032. https://dx.doi.org/10.3390/ijms10073012
Ogunwolu S O, Henshaw F O, Mock H-P, Matros A, Awonorin S O:
Radchuk V V, Borisjuk L, Sreenivasulu N, Merx K, Mock H-P, Rolletschek H, Wobus U, Weschke W:
Rapisarda P, Fabroni S, Peterek S, Russo G, Mock H-P:
Witzel K, Weidner A, Surabhi G K, Börner A, Mock H-P:
Salt stress-induced alterations in the root proteome of barley genotypes with contrasting response towards salinity. J. Exp. Bot. 60 (2009) 3545-3557. https://dx.doi.org/10.1093/jxb/erp198
Böttcher C, Centeno D, Freitag J, Höfgen R, Köhl K, Kopka J, Kroymann J, Matros A, Mock H-P, Neumann S, Pfalz M, von Roepenack-Lahaye E, Schauer N, Trenkamp S, Zubriggen M, Fernie A R:
Charakterisierung einer rekombinant in E.coli erzeugten Flavonoid-Glucosyltransferase aus Lycopersicum esculentum. (Diploma Thesis) Köthen, Hochschule Anhalt (FH) (2008) 48 pp.
Brumbarova T, Matros A, Mock H-P, Bauer P:
Butelli E, Titta L, Giorgio M, Mock H-P, Matros A, Peterek S, Schijlen E G W M, Hall R D, Bovy A G, Luo J, Martin C:
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nat. Biotechnol. 26 (2008) 1301-1308. https://dx.doi.org/10.1038/nbt.1506
Dittbrenner A, Lohwasser U, Mock H-P, Börner A:
Molecular and phytochemical studies of Papaver somniferum in the context of intraspecific classification. In: Groendijk-Wilders N, Alexander C, van den Berg R G, Hetterscheid W L A (Eds.): Proceedings of the Vth International Symposium on the Taxonomy of Cultivated Plants: Wageningen, Netherlands, October 15 - 19, 2007. (Series: Acta Horticulturae, Vol. 799) Leuven: ISHS (2008) ISBN 978-90-66055-71-1, 81-88. https://www.actahort.org/books/799/799_9.htm
Ivanov R, Tiedemann J, Czihal A, Schallau A, Diep L, Mock H-P, Claus B, Tewes A, Bäumlein H:
Etablierung einer Methode zur Isolierung mikrosomaler mRNA. (Diploma Thesis) Köthen, Hochschule Anhalt (FH) (2008) 48 pp.
Molekulare Charakterisierung von Mutanten und transgenen Linien mit veränderter Expression von Co-Chaperonen mit Homologie zum Gen At1g62740. (Diploma Thesis) Braunschweig, Technische Universität Braunschweig (2008) 69 pp.
Korn M, Peterek S, Mock H-P, Heyer A G, Hincha D K:
Etablierung einer Methode zur präparativen Aufreinigung von Anthocyanen aus Blutorangensaft mittels Festphasenextraktion. (Diploma Thesis) Jena, Fachhochschule Jena (2008) 89 pp.
Veränderungen im Proteom von Wildtyp und Mutanten der Stressproteine HIPP3 und HIPP26 bei Kälte- und Schwermetallstress. (Diploma Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg (2008) 68 pp.
Proteome analysis of cellular responses to abiotic stresses in plants. In: Agrawal G K, Rakwal R (Eds.): Plant proteomics: technologies, strategies, and applications. (Wiley-Interscience series on mass spectrometry) Hoboken, NJ: Wiley (2008) ISBN 978-0-470-06976-9, 605-628. https://dx.doi.org/10.1002/9780470369630.ch41
Proteomics der Blattseneszenz bei Arabidopsis thaliana. (Diploma Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg (2008) 86 pp.
Qualitative und quantitative Analyse von Phytosterolen in Getreide. (Diploma Thesis) Berlin, Technische Fachhochschule (2008) 97 pp.
Strickert M, Witzel K, Keilwagen J, Mock H-P, Schneider P, Biehl M, Villmann T:
Adaptive matrix metrics for attribute dependence analysis in differential high-throughput data. In: Ahdesmäki M, Strimmer K, Radde N, Rahnenführer J, Klemm K, Lähdesmäki H, Yli-Harja O (Eds.): 5th International Workshop on Computational Systems Biology, WCSB 2008, June 11–13, 2008, Leipzig, Germany, proceedings. (TICSP series, Vol. 41) Tampere: Tampere International Center for Signal Processing (2008) ISBN 978-952-15-1988-8, 181-184.
Tiedemann J, Rutten T, Mönke G, Vorwieger A, Rolletschek H, Meissner D, Milkowski C, Petereck S, Mock H-P, Zank T, Bäumlein H:
Toufektsian M C, Lorgeril M, Nagy N, Salen P, Donati M B, Giordano L, Mock H-P, Peterek S, Matros A, Petroni K, Pilu R, Rotilio D, Tonelli C, de Leiris J, Boucher F, Martins C:
Chronic dietary intake of plant-derived anthocyanins protects the rat heart against ischemia-reperfusion injury. J. Nutr. 138 (2008) 747-752.
A proteomic approach to investigate agronomic traits in barley using the genetic variation of mapping populations. (PhD Thesis) Halle/S., Martin-Luther-Universität Halle-Wittenberg (2008) 143 pp.
Bartels A, Mock H-P, Papenbrock J:
Böer E, Steinborn G, Matros A, Mock H-P, Gellissen G, Kunze G:
Production of interleukin-6 in Arxula adeninivorans, Hansenula polymorpha and Saccharomyces cerevisiae by applying the wide-range yeast vector (CoMedTM) system to simultaneous comparative assessment. FEMS Yeast Res. 7 (2007) 1181-1187. https://dx.doi.org/10.1111/j.1567-1364.2007.00254.x
Gigolashvili T, Berger B, Mock H-P, Müller C, Weisshaar B, Flügge U I:
Charakterisierung von einem Stress-induzierten Protein aus Nicotiana tabacum mit Homologie zum Gen At1g62740. (Master Thesis) Hannover, Universität Hannover (2007) 71 pp.
Tocopherol composition of plants and their regulation. In: Preedy V R, Watson R R (Eds.): The encyclopedia of vitamin E. Wallingford: CAB International (2007) ISBN 978-1-8459-3075-2, 112-121.
Etablierung einer Methode zur Anreicherung und Trennung phosphorylierter Proteine aus Gesamtblattproteinextrakten von Arabidopsis thaliana. (Diploma Thesis) Köthen, Hochschule Anhalt (FH) (2007) 110 pp.
Strickert M, Witzel K, Mock H-P, Schleif F-M, Villmann T:
Supervised attribute relevance determination for protein identification in stress experiments In: Proceedings of the International Workshop on Machine Learning in Systems Biology (MLSB 2007) (2007) 81-86.
Vorwieger A, Gryczka C, Czihal A, Douchkov D, Tiedemann J, Mock H-P, Jakoby M, Weisshaar B, Saalbach I, Bäumlein H:
Weschke W, Mock H-P, Pietsch C, Radchuk V, Röder M S, Schreiber F, Seiffert U, Sreenivasulu N, Strickert M, Witzel K, Wobus U:
Genetical Genomics der Gerstenkornentwicklung - von der Genexpression zu landwirtschaftlich bedeutsamen Merkmalen. GenomXPress 1 (2007) 12-16.
Witzel K, Surabhi G K, Jyothsnakumari G, Sudhakar C, Matros A, Mock H-P:
Quantitative proteome analysis of barley seeds using ruthenium(II)-tris-(bathophenanthroline-disulphonate) staining. J. Proteome Res. 6 (2007) 1325-1333. https://dx.doi.org/10.1021/Pr060528o
Wobus U, Mock H-P, Pietsch C, Radchuk V, Röder M, Schreiber F, Seiffert U, Sreenivasulu N, Strickert M, Weschke W, Witzel K:
GABI-SEED: Genetische Grundlagen komplexer agronomischer Merkmale im Getreidekorn entschlüsseln. GenomXPress Sonderausgabe März (2007) 19.
Amme S, Matros A, Schlesier B, Mock H-P:
Chromatographische Untersuchungen zu zellulären Schutzmechanismen gegen UV-Stress bei Gerste. (Diploma Thesis) Magdeburg, Fachhochschule Magdeburg-Stendal (2006) 61 pp.
Matros A, Amme S, Kettig B, Buck-Sorlin G H, Sonnewald U, Mock H-P:
Growth at elevated CO2 concentrations leads to modified profiles of secondary metabolites in tobacco cv. SamsunNN and to increased resistance against infection with potato virus Y. Plant Cell Environ. 29 (2006) 126-137. https://dx.doi.org/10.1111/j.1365-3040.2005.01406.x
Reiss E, Schlesier B, Brandt W:
Rossignol M, Peltier J B, Mock H-P, Matros A, Maldonado A M, Jorrin J V:
Protein isolation and second-dimension electrophoretic separation. In: Salinas J, Sanchez-Serrano J J (Eds.): Arabidopsis protocols, 2nd ed. (Series: Methods in molecular biology, Vol. 323) Totowa, N J: Humana Press (2006) ISBN 1-588-29395-5, 381-391. https://dx.doi.org/10.1385/1-59745-003-0:381
Strickert M, Czauderna T, Peterek S, Matros A, Mock H-P, Seiffert U:
Full-length HPLC signal clustering and biomarker identification in tomato plants. In: Ruan D, Dhondt P, Fantoni P F, de Cock M, Nachtegael M, Kerre E E (Eds.): Applied artificial intelligence: Proceedings of the 7th International FLINS Conference, Genova, Italy, 29-31 August 2006. Singapore [u.a.]: World Scientific (2006) ISBN 981-256-690-2, 549-556.
Strickert M, Sreenivasulu N, Peterek S, Weschke W, Mock H-P, Seiffert U:
Unsupervised feature selection for biomarker identification in chromatography and gene expression data. In: Schwenker F, Marinai S (Eds.): Artificial neural networks in pattern recognition: second IAPR Workshop, ANNPR 2006, Ulm Germany, August 31 - September 2, 2006. proceedings. (Series: Lecture Notes in Computer Science, Vol. 4087) Berlin [u.a.]: Springer (2006) ISBN 978-3-540-37951-5, 274-285. https://dx.doi.org/10.1007/11829898_25
Zimmermann G, Bäumlein H, Mock H-P, Himmelbach A, Schweizer P: